Dr. Keole currently serves as chief of Proton Radiation services at Mayo Clinic in Arizona. Dr. Keole served at the University of Florida College of Medicine, where he served as a faculty member and physician, as it was developing the University of Florida Proton Therapy Institute (UFPTI). He treated the first pediatric patient at UFPTI a month after its August 2006 opening. Dr. Keole previously served as a staff physician at Wayne State University’s Detroit Medical Center, where he worked with neutron irradiation. This sparked his interest in hadron therapy, an emerging cancer therapy, particularly in the setting of pediatric, central nervous system and genitourinary malignancies. His interests include the application of image guidance in proton therapy related to pediatric central nervous system tumors and the role of protons for prostate cancer.